参考文献：

[1] HUANG Y, WANG Y, WANG H, et al. Prevalence ofmental disorders in China: a cross-sectional epidemiological study [J]. Lancet Psychiatry, 2019, 6(3): 211-224.

[2] MARX W, LANE M, HOCKEY M, et al. Diet and depression: exploring the biological mechanisms of action [J]. Mol Psychiatry, 2021, 26(1):

134-150.

[3] LEE D H, LEE J Y, HONG D Y, et al.

Pharmacological Treatment for Neuroinflammation in Stress-Related Disorder [J]. Biomedicines, 2022, 10(10).

[4] PETRALIA M C, MAZZON E, FAGONE P, et al. The cytokine network in the pathogenesis of major depressive disorder. Close to translation? [J]. Autoimmunity Reviews, 2020, 19(5): 15.

[5] DONOSO F, EGERTON S, BASTIAANSSEN T F S, et al. Polyphenols selectively reverse early-life stress-induced behavioural, neurochemical and microbiota changes in the rat [J].

Psychoneuroendocrinology, 2020, 116: 104673.

[6] ROMAN M, IRWIN M R. Novel neuroimmunologic therapeutics in depression: A clinical

perspective on what we know so far [J]. Brain Behavior and Immunity, 2020, 83: 7-21.

[7] ERJAVEC G N, SAGUD M, PERKOVIC M N, et al. Depression: Biological markers and treatment [J]. Progress in Neuro-Psychopharmacology &

Biological Psychiatry, 2021, 105: 19.

[8] HERMAN F J, PASINETTI G M. Principles of

inflammasome priming and inhibition:

Implications for psychiatric disorders [J]. Brain Behav Immun, 2018, 73: 66-84.

[9] RICHARDS E M, ZANOTTI-FREGONARA P, FUJITA M, et al. PET radioligand binding to translocator protein (TSPO) is increased in unmedicated

depressed subjects [J]. Ejnmmi Research, 2018, 8: 9.

[10] LI H, SAGAR A P, KERI S. Translocator protein (18 kDa TSPO) binding, a marker of microglia, is reduced in major depression during

cognitive-behavioral therapy [J]. Progress in

Neuro-Psychopharmacology & Biological Psychiatry 2018, 83: 1-7.

[11] 万腾, 高雪, 刘顺峰, et al. 小胶质细胞极化与抑郁症关系的研究进展（英文） [J]. 生物化学与生物物理进展, 2021, 48(12): 1404-1413.

[12] BORIERO D, CARCERERI DE PRATI A, ANTONINI L, et al. The anti-STAT1 polyphenol myricetin

inhibits M1 microglia activation and counteracts neuronal death [J]. Febs j, 2021, 288(7):

2347-2359.

[13] GU X H, XU L J, ZHENG L L, et al. Long

non-coding RNA uc.80- overexpression promotes M2 polarization of microglias to ameliorate

depression in rats [J]. IUBMB Life, 2020, 72(10): 2194-2203.

[14] LI M X, ZHENG H L, LUO Y, et al. Gene

deficiency and pharmacological inhibition of

caspase-1 confers resilience to chronic social defeat stress via regulating the stability of surface AMPARs [J]. Molecular Psychiatry, 2018, 23(3): 556-568.

[15] INSERRA A, MASTRONARDI C A, ROGERS G, et al. Neuroimmunomodulation in Major Depressive

Disorder: Focus on Caspase 1, Inducible Nitric Oxide Synthase, and Interferon-Gamma [J]. Mol Neurobiol, 2019, 56(6): 4288-4305.

[16] LI Z, HUANG Z, ZHANG H, et al. P2X7 Receptor Induces Pyroptotic Inflammation and Cartilage Degradation in Osteoarthritis via NF-κB/NLRP3 Crosstalk [J]. Oxid Med Cell Longev, 2021, 2021: 8868361.

[17] IWATA M, OTA K T, LI X Y, et al. Psychological Stress Activates the Inflammasome via Release of Adenosine Triphosphate and Stimulation of the Purinergic Type 2X7 Receptor [J]. Biol Psychiatry 2016, 80(1): 12-22.

[18] LIU L R, LIU J C, BAO J S, et al. Interaction of Microglia and Astrocytes in the Neurovascular Unit [J]. Front Immunol, 2020, 11: 1024.

[19] TALIFU Z, LIU J Y, PAN Y Z, et al. In vivo astrocyte-to-neuron reprogramming for centralnervous system regeneration: a narrative review [J]. Neural Regen Res, 2023, 18(4): 750-755.

[20] TAMARU T, KOBAYAKAWA K, SAIWAI H, et al. Glial scar survives until the chronic phase by

recruiting scar-forming astrocytes after spinal cord injury [J]. Exp Neurol, 2023, 359: 114264.

[21] KWON H S, KOH S H. Neuroinflammation in

neurodegenerative disorders: the roles of

microglia and astrocytes [J]. Transl Neurodegener, 2020, 9(1): 42.

[22] MARINA N, CHRISTIE I N, KORSAK A, et al. Astrocytes monitor cerebral perfusion and control systemic circulation to maintain brain blood flow [J]. Nat Commun, 2020, 11(1): 131.

[23] 何沙潼, 蒋梦若, 陈嘉豪, et al. 抑郁的中枢神经炎症机制相关研究进展 [J]. 生命的化学, 2022, 42(07): 1315-1321.

[24] CHENG T, XU Z, MA X. The role of astrocytes in neuropathic pain [J]. Front Mol Neurosci, 2022, 15: 1007889.

[25] WOHLEB E S, FRANKLIN T, IWATA M, et al.

Integrating neuroimmune systems in the

neurobiology of depression [J]. Nat Rev Neurosci, 2016, 17(8): 497-511.

[26] HAN M, YUAN L, HUANG Y, et al. Integrated co-expression network analysis uncovers novel tissue-specific genes in major depressive

disorder and bipolar disorder [J]. Front Psychiatry, 2022, 13: 980315.

[27] PRICE R B, DUMAN R. Neuroplasticity in cognitive and psychological mechanisms of

depression: an integrative model [J]. Mol Psychiatry, 2020, 25(3): 530-543.

[28] PLANCHEZ B, SURGET A, BELZUNG C. Adult

hippocampal neurogenesis and antidepressants

effects [J]. Curr Opin Pharmacol, 2020, 50: 88-95.

[29] DURAZZO A, LUCARINI M, SOUTO E B, et al. Polyphenols: A concise overview on the chemistry, occurrence, and human health [J]. Phytother Res, 2019, 33(9): 2221-2243.

[30] OFOSU F K, DALIRI E B M, ELAHI F, et al. New

Insights on the Use of Polyphenol s as Natural Preservatives and Their Emerging Safety Concerns [J]. Frontiers in Sustainable Food Systems, 2020, 4: 14.